site stats

Taut gene

WebThe disruption of TauT function by either pharmacologic agents or its genetic invalidation (TauT KO mice) induces severe taurine depletion in the plasma leading to undetectable taurine concentrations in some tissues. This effect is probably a consequence of taurine uptake inhibition at the intestinal level. WebDec 28, 2001 · Taut gene disruption by homologous recombination. A) Scheme of the wild-type taut locus, the targeting (replacement) vector, and the predicted structure of the …

Disruption of the taurine transporter gene (taut) leads to retinal ...

WebMar 20, 2003 · We have recently shown that TauT is a target gene of p53, and that it is negatively regulated by p53 in renal cells. These findings strongly support the role of TauT in renal development, since overexpression of p53 in p53 transgenic mice results in severe renal damage, which is similar to the observations made in the taurine-deficient cats [3 ... WebThe TauT transporter ( SLC6A6 gene) is considered the major transporter, which is characterized by its dependence on ions (sodium or chloride), the high affinity and the … tema parenting anak sd https://htawa.net

6533 - Gene ResultSLC6A6 solute carrier family 6 …

WebAug 30, 2024 · Taurine transporter (TauT) has been identified as a target gene of p53 tumor suppressor and Wilms’ tumor suppressor gene, as well as c-Jun and c-Myc oncogenes (Han et al. 2006), respectively. TauT is also found to be overexpressed in variety type of human cancers, such as leukemia (Learn et al. 1990 ). Webtauto-: prefix meaning "same": tautomenial, tautomeral, tautomerism. WebGene: Taurine Transporter (TAUT) Species: Human Vector type: Bacterial Expression Vector Vector backbone: pPB-His-MBP Resistance Gene: Kanamycin Promoter: T7 … tema parenting tk

Osmoregulation of TauT is mediated by JNK signaling

Category:Disruption of the taurine transporter gene (taut) leads to retinal ...

Tags:Taut gene

Taut gene

Taurine transporter in fetal T lymphocytes and platelets: …

WebTau is a phosphoprotein with 79 potential Serine (Ser) and Threonine (Thr) phosphorylation sites on the longest tau isoform. Phosphorylation has been reported on approximately 30 of these sites in normal tau … WebJan 4, 2002 · Gene expression of TauT and taurine biosynthetic enzymes was estimated by measuring TauT, CDO, and CSD mRNA levels in cell RNA extracts through RT-PCR assays that we have developed according to published cDNA sequences of TauT ( 27 ), CDO ( 12 ), and CSD ( 29 ). MATERIALS AND METHODS Astrocyte primary cultures

Taut gene

Did you know?

WebTauT (along with system A) plays a cytoprotective role in stressed syncytiotrophoblasts. TauT-knockdown using siRNA revealed that TauT is a major contributor to taurine uptake by TR-TBT 18d-1 cells under normal conditions. prevents cardiomyocyte death by inhibiting NADPH oxidase-mediated calpain activation WebRepression of TauT expression by stable transfection of ts p53 in renal cells. NRK-52E/ts p53 cells were cultured at 37 or 32 °C for 24 h, and then cells were prepared for Northern blot, Western ...

WebOct 18, 2002 · To determine whether down-regulation of the TauT gene by p53 occurs at the transcriptional level, the reporter construct pGL-963, containing a putative p53-binding site from −663 to −695 (Fig. 4 A), was transiently transfected into 293, NRK-52E, and (10)1 cells.Regulation ofTauT promoter function by p53 was examined in cells treated with … WebDec 3, 2013 · The GAT group, which has been well studied in mammals, has 6 known members, i.e., a taurine transporter (TAUT), four GABA transporters (GAT-1, -2, -3, - 4), …

WebMar 21, 2024 · This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein … WebMar 12, 2024 · The amino acid taurine is highly abundant in brain, liver, and other organs ().Intracellular taurine concentrations are maintained at high levels through uptake by the taurine transporter TauT ().Functions of …

WebOct 18, 2002 · To determine whether down-regulation of the TauT gene by p53 occurs at the transcriptional level, the reporter construct pGL-963, containing a putative p53 …

WebJan 28, 2015 · Our results demonstrated that both homozygous and heterozygous TauT gene deletion predispose C57BL/6 mice to develop end-stage diabetic kidney disease, which closely replicates the pathological ... tema parkWebAug 15, 2004 · TauT promoter activity is regulated through a TonE/TonEBP pathway ( A) Cells were transfected with p2xTonE-Luc. Cells were cultured 24 h after transfection in isotonic (iso) or hypertonic media (NaCl+50 or Suc 100) for 24 h. Results were obtained from three experiments. tema park 2WebWe have demonstrated that cisplatin down-regulates the expression of the taurine transporter gene (TauT) in renal cells and that forced overexpression of TauT protects against... temaparkerWebDefine taut. taut synonyms, taut pronunciation, taut translation, English dictionary definition of taut. trim; tidy; tense: She speaks in short, taut sentences. Not to be confused with: … tema park cataniaWebGene Hackman, Kevin Costner, SEAN Young. ... In this taut remake of "The Big Clock," a Naval intelligence officer assigned to investigate a murder is horrified to find out that the victim is his girlfriend - and that he's being framed … temapartyWebIn order to clone the upstream region of the human TAUT promoter, we have compared TAUT cDNA sequences with the entire human genome sequence. Polymerase chain reaction (PCR) was performed from genomic DNA prepared from a SK-Hep-1 cell line for the amplification of the TAUT promoter region including the partial exon (150 bp) and the 5 ... tema pasepWebJan 1, 2007 · TAUT and β-actin (housekeeping gene used to confirm amplification capacity) mRNA was quantified by real-time quantitative PCR using intercalation of SYBR Green as described previously . All reactions were run in duplicate and 5-carboxy-x-rhodamine was included as passive reference dye. tema parker