Mammary acini
WebIn addition, Bissell and coworkers have shown that inhibition of the hyperactive Erk kinase pathway in 3D cultures of transformed human mammary epithelial cells induces … Web10 jan. 2024 · Acini cultures recapitulate important characteristics of the normal mammary gland, namely single cell-layered structures, proliferation arrest (90–95% Ki67-negative …
Mammary acini
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Web19 okt. 2016 · Non-malignant mammary epithelial cells (MECs), such as MCF10A, grown in reconstituted basement membrane extract, commercially available as Matrigel, form … WebHere we show that mammary acini with compromised structural integrity can interconnect by forming long collagen lines. These collagen lines then coordinate and accelerate …
WebIdentify and describe the histological differences between the mammary gland in adult females prior to pregnancy (inactive), during pregnancy and during lactation (active). … Web13 okt. 2024 · In this study we analysed the mutual interaction of different matrix stiffnesses and MRTF-A activities on formation and maintenance of mammary acini. Methods: …
WebBreast Acini The acini of the breast glands contain secretory, epithelial cells with an outer layer of myoepithelial cells. Note the vacuolated appearance of the cytoplasm of the … WebWithin the mammary gland, epithelial cells are organized into spherical structures with a lumen, termed acini, which produce milk that is transported to the nipple through a …
Web1 apr. 1987 · Protein synthesis in the rat mammary gland has been studied using acini isolated from mammary tissue by collagenase digestion. When the acini were inc…
Web15 aug. 2024 · MCF10A acini grown in 3D Matrigel recapitulate normal apicobasal polarity, secrete endogenous basement membrane proteins (including laminin V and type IV … mysophos アカウントWeb30 dec. 2013 · Mechanical remodeling of collagen substrates by mammary acini. (A) Schematic of experiment. Acini are placed on collagen 1 gels and subsequent … mysonyid ログインWeb21 jul. 2024 · Here we present a novel model of breast tumorigenesis where only single cells express oncogenes within healthy mammary acini and are able to establish localized … mysos ご利用になる国とは 知恵袋Web1 jul. 2003 · Morphological architecture of mammary gland in vivo and MCF-10A acini in vitro. (A) Schematic (left) of a lobule from human mammary gland; mammary epithelium … mysonyid メールアドレス変更Web15 aug. 2014 · We previously described a novel unsupervised strategy to identify predictive signatures for breast cancer using 3D culture models of differentiating non-malignant … mysos アカウント登録 方法Web8 mrt. 2024 · (1) Delineated the role of nitric oxide production in regulating cellular physiology and cytoskeletal structures during mammary acinar formation in 3D culture … mysos アカウント登録方法Web7 jun. 2024 · MRTF activation during MCF10A acinar morphogenesis. To investigate processes involved in acinar morphogenesis we cultured human mammary MCF10A … mysos pdf アップロード