Cisplatin and cancer
WebApr 22, 2024 · Cancer cells repeatedly challenge researchers with their ability to develop resistance to treatments that were effective to begin with. Resistance to cisplatin, a … WebTreatment of lung cancer, the most common type of carcinoma, is difficult due to disease progression at the time of diagnosis, causing a high mortality rate. 1, 32 Cisplatin …
Cisplatin and cancer
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WebApr 13, 2024 · Testicular cancer, also known as testicular germ cell tumors (TGCT), is the most common type of cancer in young men. When treated with cisplatin, the tumor cells … WebMar 25, 2024 · Here, we report that RRS1 is associated with cisplatin resistance in breast cancer cells. RRS1 silencing increased the sensitivity of MCF-7/DDP cells to cisplatin and inhibited cancer cell proliferation by blocking cell cycle distribution and enhancing apoptosis. AEG-1 (astrocyte elevated gene-1) promotes drug resistance by interfering with the ...
WebSquamous-cell carcinoma of the head and neck accounts for 5% of newly diagnosed cancers in adults in the United States and 8% of cancers worldwide. 1 The disease is potentially curable at an early...
WebObjectives: Cisplatin-induced ototoxicity is a common permanent consequence of curative chemoradiation for locally advanced head and neck squamous cell carcinoma (HNSCC). Predictors of ototoxicity in HNSCC were examined. Materials and methods: In this prospective, observational cohort study, 206 adult HNSCC patients underwent … WebJul 14, 2014 · A critical aspect of the activity of platinum drugs in vitro and in vivo is their interaction with the solvent environment. For example, platinum drugs are activated via replacement of leaving groups with water inside the cell, a process termed aquation ().For cisplatin, this is the loss of a chloride ligand and its replacement with water, which is a …
WebDec 12, 2024 · A type of blood cancer (leukemia) has happened after treatment with this drug. If you have questions, talk with the doctor. If you are 65 or older, use this drug with care. You could have more side effects. If the patient is a child, use this drug with care. The risk of some side effects may be higher in children. This drug may affect fertility.
WebDec 7, 2024 · Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive disease with poor survival, and platinum-etoposide chemotherapy is indicated as the mainstay of treatment. In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens. Methods fish in yorubaWebDec 12, 2024 · A type of blood cancer (leukemia) has happened after treatment with this drug. If you have questions, talk with the doctor. If you are 65 or older, use this drug with … fish in youtubeWebTreatment of lung cancer, the most common type of carcinoma, is difficult due to disease progression at the time of diagnosis, causing a high mortality rate. 1 , 32 Cisplatin (DDP), also known as cis‐diaminodichloplatin, is a powerful nonspecific drug blocking the cell cycle. 33 , 34 DDP can enter cells through the passive transport. fish in your dreamsWebCisplatin or (SP-4-2)-diamminedichloridoplatinum(II) is one of the most potential and widely used drugs for the treatment of various solid cancers such as testicular, ovarian, head … can chickens have sweet potato peelsWeb2 days ago · Testicular cancer, also known as testicular germ cell tumors (TGCT), is the most common type of cancer in young men. When treated with cisplatin, the tumor cells … can chickens have sexWebBackground. Phase 2 studies suggest that the standard regimen of cisplatin and fluorouracil (PF) plus docetaxel (TPF) improves outcomes in squamous-cell carcinoma of the head and neck. We compared ... can chickens have strawberry topsWebBEP (bleomycin, etoposide, and cisplatin) for 3 or 4 cycles VIP (etoposide, ifosfamide, and cisplatin) for 4 cycles If there's a high suspicion that the cancer might be a testicular choriocarcinoma, chemo may be started without a biopsy or surgery to remove the testicle. fish in your diet